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Peptide record

TPDB41155

P-5m GHGKHKNK Anticancer Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB41155
P-5m GHGKHKNK
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 8-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
GHGKHKNK
Physicochemical Analysis
C38H64N16O10
ARDCEQILMFPSTWYV
K
905.03
10.84
5
0
0
+3
5.33
-2.800
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
2
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 2 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C38H64N16O10
905.03
10.84
+3
5.33
-2.800
HGK
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Lung metastassis
Vitronectin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Effect of His-Gly-Lys motif derived from domain 5 of high molecular weight kininogen on suppression of cancer metastasis both in vitro and in vivo
2003
Kawasaki M et al. J Biol Chem. 2003 Dec 5 278(49):49301-7.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231 cells
Mice bearing malignant melanoma cell line B16-F10 derived tumor
Natural(Kininogen protein)
Additional Detail Fields 2 fields
MDA-MB-231 cells
Mice bearing malignant melanoma cell line B16-F10 derived tumor