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Peptide record

TPDB41142

MAC1/20 Anticancer Antifungal modified_plain modified
13 source-reported length (unverified)
Basic Information
TPDB41142
MAC1/20
Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
CancerPPD 2.0 Peptipedia SATPdb dbACP CAFPdb
modified_plain
Yes
A modified multi-activity (Anticancer and Antifungal) peptide record curated from CancerPPD 2.0, Peptipedia, SATPdb, and other sources, without an available 3D structural model. Source-reported length: 13 (unverified).
C-terminal: Amidation Chemical: O = Ornithine
Sequence
GFGMALOLLOOVL-NH2

Source notation is retained verbatim; residue notation and chemical identity have not been independently validated. The displayed length is source-reported and unverified.

Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
13 source-reported length (unverified)
Amidation Activity
O = Ornithine Activity
L Activity
Linear Activity
Free Activity
Antimicrobial and Antifungal Activity
Macropins and their analogs Activity
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 10±1 µM
Anticancer
10

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT/MTS assay
48-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2012

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 35±4 µM
Anticancer
35

Target

Colon Cancer
SW
Colon

Assay & Model

MTT/MTS assay
48-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2012
Evidence 3 Activity

Activity

IC50
IC50 = 25±3 µM
Anticancer
25

Target

Leukemia Cancer
CCRF-CEM
Blood

Assay & Model

MTT/MTS assay
48-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2012