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Peptide record

TPDB41129

17BIPHE2 Anticancer modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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TPDB41129
17BIPHE2
Anticancer
Cancer-related peptides
CancerPPD 2.0
modified_plain
Yes
A 17-aa modified anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Modified, details unspecified
Sequence
GBKRLVQRLKDBLRNLV
Physicochemical Analysis
C79H146N28O20
ACEHIMFPSTWY
L
1808.20
12.13
5
1
6
+4
4.55
-0.506
125.88
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
3
R
1
N
1
D
0
C
0
E
1
Q
1
G
0
H
0
I
4
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 4 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
17
C79H146N28O20
1808.20
12.13
+4
4.55
-0.506
Free
L
Linear
Free
Antimicrobial
Derivative of LL-37
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 34.33 µmol
Anticancer
34.33 µm

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 71.42 µmol/L
Anticancer
71.42 µm

Target

Lung Cancer
NCI-H-1975
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021