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Peptide record

TPDB41128

DC2 Anticancer Antifungal standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB41128
DC2
Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
CancerPPD 2.0 Peptipedia dbACP Antifungipept
standard
No
A 31-aa standard natural multi-activity (Anticancer and Antifungal) peptide sequence curated from CancerPPD 2.0, Peptipedia, dbACP, and other sources, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
GAVPCGETCVYLPCITPDIGCSCQNKVCYRD
Physicochemical Analysis
C138H219N37O45S6
HMFW
C
3308.84
4.31
2
3
9
-1
4.61
0.177
69.03
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
101.40
13
Residue Composition
number
1
A
1
R
1
N
2
D
6
C
1
E
1
Q
3
G
0
H
2
I
1
L
1
K
0
M
0
F
3
P
1
S
2
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 2 C: 6 E: 1 Q: 1 G: 3 H: 0 I: 2 L: 1 K: 1 M: 0 F: 0 P: 3 S: 1 T: 2 W: 0 Y: 2 V: 3
Chemical Descriptors
31
C138H219N37O45S6
3308.84
4.31
-1
4.61
0.177
Cyclized
L
Cyclic
Cyclized
Anticancer
Hedyotis diffusa
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 4.31 µM
Anticancer
4.31 µM

Target

Prostate Cancer
LNCaP
Prostate

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 2.65 µM
Anticancer
2.65 µM

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015
Evidence 3 Activity

Activity

IC50
IC50 = 3.11 µM
Anticancer
3.11 µM

Target

Liver Cancer
DU-145
Liver

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015