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Peptide record

TPDB41122

DC1 Anticancer Antifungal standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB41122
DC1
Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
CancerPPD 2.0 Peptipedia dbACP Antifungipept
standard
No
A 32-aa standard natural multi-activity (Anticancer and Antifungal) peptide sequence curated from CancerPPD 2.0, Peptipedia, dbACP, and other sources, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
GAFLKCGESCVYLPCLTTVVGCSCQNSVCYRD
Physicochemical Analysis
C144H228N38O46S6
HIMW
C
3419.98
5.97
2
2
11
-0
1.18
0.506
75.94
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
98.10
15
Residue Composition
number
1
A
1
R
1
N
1
D
6
C
1
E
1
Q
3
G
0
H
0
I
3
L
1
K
0
M
1
F
1
P
3
S
2
T
0
W
2
Y
4
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 6 E: 1 Q: 1 G: 3 H: 0 I: 0 L: 3 K: 1 M: 0 F: 1 P: 1 S: 3 T: 2 W: 0 Y: 2 V: 4
Chemical Descriptors
32
C144H228N38O46S6
3419.98
5.97
-0
1.18
0.506
Cyclized
L
Cyclic
Cyclized
Anticancer
Hedyotis diffusa
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 5.03 µM
Anticancer
5.03 µM

Target

Prostate Cancer
LNCaP
Prostate

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 2.24 µM
Anticancer
2.24 µM

Target

Prostate Cancer
PC-3
Prostate

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015
Evidence 3 Activity

Activity

IC50
IC50 = 3.32 µM
Anticancer
3.32 µM

Target

Liver Cancer
DU-145
Liver

Assay & Model

CCK-8 assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2015