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Peptide record

TPDB41113

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB41113
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
FTTVCRQPRGHEAIVCGSGK
Physicochemical Analysis
C90H148N30O27S2
NDLMWY
G
2146.47
9.15
4
1
5
+2
5.11
-0.280
53.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
5.82
6
Residue Composition
number
1
A
2
R
0
N
0
D
2
C
1
E
1
Q
3
G
1
H
1
I
0
L
1
K
0
M
1
F
1
P
1
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 2 E: 1 Q: 1 G: 3 H: 1 I: 1 L: 0 K: 1 M: 0 F: 1 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C90H148N30O27S2
2146.47
9.15
+2
5.11
-0.280
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library