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Peptide record

TPDB41094

SKACP003 Anticancer Neuropeptide standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB41094
SKACP003
Anticancer Neuropeptide
Cancer-related peptides Neuroactive peptides
CancerPPD 2.0 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Anticancer and Neuropeptide) peptide sequence curated from CancerPPD 2.0 and Peptipedia, with an available 3D structural model.
Sequence
FPLPCAYKGTYC
Physicochemical Analysis
C64H91N13O16S2
RNDEQHIMSWV
CPY
1362.62
8.27
1
0
5
+1
-2.18
0.217
40.83
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
3105
227.87
5
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
1
L
1
K
0
M
1
F
2
P
0
S
1
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 1 M: 0 F: 1 P: 2 S: 0 T: 1 W: 0 Y: 2 V: 0
Chemical Descriptors
12
C64H91N13O16S2
1362.62
8.27
+1
-2.18
0.217
Free
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 193 ± 0.5 µM
Anticancer
193

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 212 ± 0.5 µM
Anticancer
212

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021
Evidence 3 Activity

Activity

IC50
IC50 = 156 ± 0.5 µM
Anticancer
156

Target

Breast Cancer
MDA-MB-453
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021