TPDB

3D PDB MODEL

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TPDB ID TPDB41089

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0

Sequence_Type

standard

Has_Modification No

Description A 22-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.

Sequence

FLSGIVGMLAKLFLFKQYAELW

FASTA

>TPDB41089|Anticancer|length=22
FLSGIVGMLAKLFLFKQYAELW

Formula C128H192N26O28S1

Absent Amino Acids RNDCHPT

Common Amino Acids L

Mass 2575.15

PI 9.65

Basic Residues 2

Acidic Residues 1

Hydrophobic Residues 15

Net Charge +1

Boman Index -5.06

Hydrophobicity 1.045

Aliphatic Index 128.64

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 6990

Absorbance 280nm 271.44

Polar Residues 3

number

2

A

0

R

0

N

0

D

0

C

1

E

1

Q

2

G

0

H

1

I

5

L

2

K

1

M

3

F

0

P

1

S

0

T

1

W

1

Y

1

V

Amino Acid Distribution

A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 2 H: 0 I: 1 L: 5 K: 2 M: 1 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 1 V: 1

Length

22

Formula

C128H192N26O28S1

Mass

2575.15

PI

9.65

Net Charge

+1

Boman Index

-5.06

Hydrophobicity

1.045

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.