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Peptide record

TPDB41077

Sample Peptide 4 from US011339203B2 Anticancer standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB41077
Sample Peptide 4 from US011339203B2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 35-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
FLLISACWVISLILGGLPIMGWKKRTLRKNDRKKR-NH2
Physicochemical Analysis
C190H321N55O42S2
EQHY
L
4112.10
12.01
9
1
16
+8
0.72
0.074
122.57
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
267.50
5
Residue Composition
number
1
A
4
R
1
N
1
D
1
C
0
E
0
Q
3
G
0
H
4
I
6
L
5
K
1
M
1
F
1
P
2
S
1
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 4 N: 1 D: 1 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 4 L: 6 K: 5 M: 1 F: 1 P: 1 S: 2 T: 1 W: 2 Y: 0 V: 1
Chemical Descriptors
35
C190H321N55O42S2
4112.10
12.01
+8
0.72
0.074
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell Viability
Cell Viability = 85.6% at 25 µM
Anticancer

Target

Renal Cancer
CAKI-2
Kidney

Assay & Model

CCK-8 assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
US011339203B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.