Back to search

Peptide record

TPDB41074

NAF-1 Anticancer Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB41074
NAF-1
Anticancer Cell-penetrating Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CancerPPD 2.0 CPPsite3.0
standard
No
A 24-aa standard natural multi-activity (Anticancer and Cell-penetrating Peptides) peptide sequence curated from CancerPPD 2.0 and CPPsite3.0, with an available 3D structural model.
Sequence
FLGVLALLGYLAVRPFLPKKKQQK
Physicochemical Analysis
C133H219N33O28
NDCEHIMSTW
L
2728.41
11.04
5
0
13
+5
0.09
0.333
130.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
54.61
3
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
2
Q
2
G
0
H
0
I
6
L
4
K
0
M
2
F
2
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 0 I: 0 L: 6 K: 4 M: 0 F: 2 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
24
C133H219N33O28
2728.41
11.04
+5
0.09
0.333
Free
L
Linear
Free
Anticancer
NAF-1/CISD2
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 18.3 ± 0.4 µM
Anticancer
18.3

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.