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Peptide record

TPDB41071

AP1-Z3b Anticancer standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB41071
AP1-Z3b
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 18-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Amidation
Sequence
FLFSLIKHAISKLISAFK-NH2
Physicochemical Analysis
C102H163N23O22
RNDCEQGMPTWYV
ILKFS
2063.56
10.84
4
0
11
+3
-2.02
1.089
141.11
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
3
I
3
L
3
K
0
M
3
F
0
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 3 L: 3 K: 3 M: 0 F: 3 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C102H163N23O22
2063.56
10.84
+3
-2.02
1.089
Amidation
L
Linear
Amidation
Antimicrobial
Mutant of APR-Z1
Evidence Records 3 records
Evidence 1 Activity

Activity

Graph Figure 2A
Anticancer

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Graph Figure 2B
Anticancer

Target

Skin Cancer
A-375
Skin

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019
Evidence 3 Activity

Activity

Graph Figure 2C
Anticancer

Target

Brain Tumor
U-87
Brain

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019