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Peptide record

TPDB41069

AP1-Z9 Anticancer standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB41069
AP1-Z9
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 18-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Amidation
Sequence
FLFKLIKKKIKKLIKKFK-NH2
Physicochemical Analysis
C117H203N27O19
ARNDCEQGHMPSTWYV
K
2292.07
11.41
9
0
9
+9
2.91
-0.100
130.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
3
L
9
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 3 K: 9 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C117H203N27O19
2292.07
11.41
+9
2.91
-0.100
Amidation
L
Linear
Amidation
Antimicrobial
Mutant of APR-Z1
Evidence Records 3 records
Evidence 1 Activity

Activity

Graph Figure 2A
Anticancer

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Graph Figure 2B
Anticancer

Target

Skin Cancer
A-375
Skin

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019
Evidence 3 Activity

Activity

Graph Figure 2C
Anticancer

Target

Brain Tumor
U-87
Brain

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019