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Peptide record

TPDB41067

BmPLA2 Anticancer standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB41067
BmPLA2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 24-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
FKWQFEMLIMKIAKTSGFMFYSSY
Physicochemical Analysis
C144H207N29O34S3
RNDCHPV
F
2984.58
9.89
3
1
14
+2
-4.18
0.242
52.92
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
8480
284.13
7
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
1
G
0
H
2
I
1
L
3
K
3
M
4
F
0
P
3
S
1
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 0 I: 2 L: 1 K: 3 M: 3 F: 4 P: 0 S: 3 T: 1 W: 1 Y: 2 V: 0
Chemical Descriptors
24
C144H207N29O34S3
2984.58
9.89
+2
-4.18
0.242
Free
L
Linear
Free
Anticancer
phospholipase A2 isoform from B. moojeni venom
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 0.6 µM
Anticancer
0.6 µM

Target

Colorectal Cancer
CaCo-2
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

60% reduction in cell viability
Anticancer

Target

Rhabdomyosarcoma
RD
Muscle

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022