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Peptide record

TPDB41064

Loop1-HCoV-229E Anticancer standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB41064
Loop1-HCoV-229E
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 11-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
FKPQSGGGKCF-NH2
Physicochemical Analysis
C52H78N14O14S1
ARNDEHILMTWYV
G
1155.34
9.90
2
0
2
+2
0.67
-0.618
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
1
Q
3
G
0
H
0
I
0
L
2
K
0
M
2
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 3 H: 0 I: 0 L: 0 K: 2 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C52H78N14O14S1
1155.34
9.90
+2
0.67
-0.618
Amidation
L
Linear
Free
Anticancer
Alphacoronavirus (HCoV-229E)
Evidence Records 1 records
Evidence 1 Activity

Activity

EC50
EC50 = 125.0 ± 1.32 µM
Anticancer
125.0

Target

Colorectal Cancer
SW-480
Colon

Assay & Model

Sulforhodamine B assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.