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Peptide record

TPDB41056

pep1 Anticancer standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB41056
pep1
Anticancer
Cancer-related peptides
AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF
standard
No
A 22-aa standard natural anticancer peptide sequence curated from AntiCP 2.0, CancerPPD 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FKCRRWQWRMKKLGAPSITCVR
Physicochemical Analysis
C123H200N40O26S3
NDEHY
R
2751.37
11.98
7
0
8
+7
1.01
-0.659
53.18
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11125
404.34
5
Residue Composition
number
1
A
4
R
0
N
0
D
2
C
0
E
1
Q
1
G
0
H
1
I
1
L
3
K
1
M
1
F
1
P
1
S
1
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 1 K: 3 M: 1 F: 1 P: 1 S: 1 T: 1 W: 2 Y: 0 V: 1
Chemical Descriptors
22
C123H200N40O26S3
2751.37
11.98
+7
1.01
-0.659
Free
L
Linear
Free
Antimicrobial
Bovine lactoferrin (Lf-B)
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50=77 µM
Anticancer
77 µM

Target

Prostate Cancer
HL-60
Blood

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.