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Peptide record

TPDB40988

mt_T18S/L22 W/P27A Anticancer standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB40988
mt_T18S/L22 W/P27A
Anticancer
Cancer-related peptides
CancerPPD 2.0 Peptipedia SATPdb dbACP
standard
No
A 12-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, Peptipedia, SATPdb, and other sources, with an available 3D structural model.
Sequence
ESFSDWWKLLAE
Physicochemical Analysis
C72H99N15O21
RNCQGHIMPTYV
ELSW
1510.67
3.83
1
3
6
-2
0.40
-0.467
73.33
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
11000
728.16
2
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
2
E
0
Q
0
G
0
H
0
I
2
L
1
K
0
M
1
F
0
P
2
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 1 M: 0 F: 1 P: 0 S: 2 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
12
C72H99N15O21
1510.67
3.83
-2
0.40
-0.467
Free
L
Linear
Free
Anticancer
MDM4
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50=27 µM
Anticancer
27 µM

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2014

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.