TPDB

3D PDB MODEL

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TPDB ID TPDB40956

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

dbACP

Sequence_Type

standard

Has_Modification No

Description A 243-aa standard natural anticancer peptide sequence curated from dbACP, with an available 3D structural model.

Sequence

EFALAYPIYTSGSTGRPKGAAVRHRSLAGCMRWMQDTYGLTRDDTVLHKAPFGFDVSVWEIFWPLTTGVRLVVANPGDHRDPERITALVRRHAVTTMNFVPPMLQAFLAHEGIERETRLRYVICGGEAMPSATQREALQRLHGVSLQNLYGPTETTIHVTQWTCRDDGRSRVPIGRPIARTQAYVLDAALNPVPAGVVGELYIGGELLARGYLGRPSLSAERFVADPVGQAGGRLYRTGDVKG

FASTA

>TPDB40956|Anticancer|length=243
EFALAYPIYTSGSTGRPKGAAVRHRSLAGCMRWMQDTYGLTRDDTVLHKAPFGFDVSVWEIFWPLTTGVRLVVANPGDHRDPERITALVRRHAVTTMNFVPPMLQAFLAHEGIERETRLRYVICGGEAMPSATQREALQRLHGVSLQNLYGPTETTIHVTQWTCRDDGRSRVPIGRPIARTQAYVLDAALNPVPAGVVGELYIGGELLARGYLGRPSLSAERFVADPVGQAGGRLYRTGDVKG

Formula C1187H1871N351O339S8

Absent Amino Acids

Common Amino Acids G

Mass 26739.54

PI 9.41

Basic Residues 35

Acidic Residues 23

Hydrophobic Residues 100

Net Charge +6

Boman Index 42.13

Hydrophobicity -0.208

Aliphatic Index 84.28

Half Life

Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 35535

Absorbance 280nm 132.89

Polar Residues 52

number

23

A

25

R

4

N

11

D

3

C

12

E

8

Q

26

G

7

H

9

I

22

L

3

K

5

M

7

F

16

P

9

S

19

T

4

W

9

Y

21

V

Amino Acid Distribution

A: 23 R: 25 N: 4 D: 11 C: 3 E: 12 Q: 8 G: 26 H: 7 I: 9 L: 22 K: 3 M: 5 F: 7 P: 16 S: 9 T: 19 W: 4 Y: 9 V: 21

Length

243

Formula

C1187H1871N351O339S8

Mass

26739.54

PI

9.41

Net Charge

+6

Boman Index

42.13

Hydrophobicity

-0.208

Evidence 1 Activity

Source & Reference

Database Source dbACP