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Peptide record

TPDB40921

Clone G3-A4 Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB40921
Clone G3-A4
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
DKPTAFVSVYLKTAL
Physicochemical Analysis
C78H125N17O22
RNCEQGHIMW
ALKTV
1652.95
9.65
2
1
8
+1
0.68
0.400
104.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
1490
90.14
4
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
2
K
0
M
1
F
1
P
1
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 2 M: 0 F: 1 P: 1 S: 1 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
15
C78H125N17O22
1652.95
9.65
+1
0.68
0.400
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell and tumor cell
Targeting
Tumor metastasis
Galectin-3

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion
2005
Zou J et al. Carcinogenesis. 2005 Feb 26(2):309-18.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 4
Phage display library
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library
Additional Detail Fields 2 fields
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 4
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library