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Peptide record

TPDB40911

caspase 3 inhibitor Anticancer standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB40911
caspase 3 inhibitor
Anticancer
Cancer-related peptides
AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF
standard
No
A 4-aa standard natural anticancer peptide sequence curated from AntiCP 2.0, CancerPPD 2.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Fluoromethyl ketone(fmk)
Sequence
DEVD
Physicochemical Analysis
C18H28N4O11
ARNCQGHILKMFPSTWY
D
476.44
2.87
0
3
1
-3
4.55
-1.575
72.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
2
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 2 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
4
C18H28N4O11
476.44
2.87
-3
4.55
-1.575
Fluoromethyl ketone(fmk)
L
Linear
Free
Anticancer
caspase 3 inhibitor
Evidence Records 3 records
Evidence 1 Activity

Activity

65% Cell viability at 20 µM
Anticancer

Target

Breast Cancer
Bcap-37
Breast

Assay & Model

MTT/MTS assay
1-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2013

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

40% Cell viability at 30 µM
Anticancer

Target

Breast Cancer
Bcap-37
Breast

Assay & Model

MTT/MTS assay
1-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2013
Evidence 3 Activity

Activity

35 % Cell viability at 40 µM
Anticancer

Target

Breast Cancer
Bcap-37
Breast

Assay & Model

MTT/MTS assay
1-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2013