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Peptide record

TPDB40881

Tritrp DiSu Anticancer standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB40881
Tritrp DiSu
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 15-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
CVRRFPWWYPFLRRC-NH2
Physicochemical Analysis
C100H141N29O17S2
ANDEQGHIKMST
R
2085.52
11.00
4
0
7
+4
-3.73
-0.380
45.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
12615
604.88
3
Residue Composition
number
0
A
4
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
2
F
2
P
0
S
0
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 2 P: 2 S: 0 T: 0 W: 2 Y: 1 V: 1
Chemical Descriptors
15
C100H141N29O17S2
2085.52
11.00
+4
-3.73
-0.380
Amidation
L
Cyclic(C1-15)
Free
Antimicrobial
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 12.3 µM
Anticancer
12.3 µM

Target

Blood Cancer
Jurkat
Blood

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.