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Peptide record

TPDB40872

Anticancer Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB40872
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia SATPdb StackTHP StackTHPred TumorHoPe2.0
standard
No
A 10-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, SATPdb, StackTHP, and other sources, with an available 3D structural model.
Sequence
CTTHWGFTLC
Physicochemical Analysis
C52H73N13O14S2
ARNDEQIKMPSYV
T
1168.35
7.00
1
0
3
-0
-2.63
0.500
39.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
481.45
5
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
1
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
3
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 3 W: 1 Y: 0 V: 0
Chemical Descriptors
10
C52H73N13O14S2
1168.35
7.00
-0
-2.63
0.500
HWGF
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Multiple tumor
MMP2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Matrix metalloproteinase inhibitors and down-regulators
2003
US 6,624,144 B1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
The HT1080 fibrosarcoma cells , C8161 melanoma cells and Eahy926 cells (derivative of HUVEC)
Mice bearing human breast carcinomas(MDA-B-435)
Phage display library
CX 9 library
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell
Targeting
Gelatinase

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease inhibitor:protease sensitive expression system, composition and methods for improving the therapeutic activity and specificity of proteins delivered by bacteria
2022
US 11219671 B1
US 11219671 B1

Other

Salmonella typhimurium
Phage display library
Ph.D-7 Phage Display
Additional Detail Fields 3 fields
The HT1080 fibrosarcoma cells , C8161 melanoma cells and Eahy926 cells (derivative of HUVEC)
Mice bearing human breast carcinomas(MDA-B-435) Salmonella typhimurium
CX 9 library Ph.D-7 Phage Display