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Peptide record

TPDB40869

TCP-1 Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB40869
TCP-1
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CTPSPFSHC
Physicochemical Analysis
C41H59N11O13S2
ARNDEQGILKMWYV
CPS
978.11
7.00
1
0
1
-0
0.65
-0.100
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.78
5
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
1
F
2
P
2
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 2 S: 2 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C41H59N11O13S2
978.11
7.00
-0
0.65
-0.100
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Lung cancer, Breast cancer, Liver cancer, Melanoma, stomach cancer, Pancreatic cancer, Colorectal cancer, Ovarian cancer, Renal cell carcinoma, Prostate cancer, Brain tumor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Noxa-derived, cell death-inducing peptide eMTD
2022
US 11248024 B2
US 11248024 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Sp2/0, CHO (Chinese hamster ovary) K1, CHO DG44, PER.C6, W138, BHK, COS7, 293, HepG2, Huh7, 3T3, RIN, MDCK cell line
6-week-old BalB/C mice
Synthetic
necrosis-inducing peptide, Fluorescein (FAM)
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel
Homing
Colorectal cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Vascular-targeted TNFα and IFNγ inhibits orthotopic colorectal tumor growth
2016
Jing Shen et al. J Transl Med. 2016 Jun 24 14(1):187.

Other

murine CRC cell Colon 26, Mouse fibroblast cell line L929
Male BALB/c mice aged 6 weeks
Phage Display Library
IFNγ, TNFα
Cyclic
Additional Detail Fields 3 fields
necrosis-inducing peptide, Fluorescein (FAM) IFNγ, TNFα
Sp2/0, CHO (Chinese hamster ovary) K1, CHO DG44, PER.C6, W138, BHK, COS7, 293, HepG2, Huh7, 3T3, RIN, MDCK cell line murine CRC cell Colon 26, Mouse fibroblast cell line L929
6-week-old BalB/C mice Male BALB/c mice aged 6 weeks