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Peptide record

TPDB40846

P1 Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB40846
P1
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CSDSWHYWC
Physicochemical Analysis
C53H63N13O15S2
ARNEQGILKMFPTV
CSW
1186.28
4.94
1
1
3
-1
-2.67
-0.711
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
12615
1063.41
5
Residue Composition
number
0
A
0
R
0
N
1
D
2
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
2
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
9
C53H63N13O15S2
1186.28
4.94
-1
-2.67
-0.711
CSDxxHxWC
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Colon cancer
VEGFR-3 (Human vascular endothelia growth factor receptor 3 )

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification of a novel peptide ligand of human vascular endothelia growth factor receptor 3 for targeted tumour diagnosis and therapy
2007
Qin X et al. J Biochem. 2007 Jul 142(1):79-85.
US 2010/0233161

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
The human colon cancer cell line (HT29),Human umbilical vein endothelial cell line (EVC304),Human retinoblastoma cell line (Y79), Human amino cell line (WISH),Human hepatic cancer cell line (HepG2),Human alveolar epithelial cell line (A549)
Phage display library
M13 phage / 7-mer peptide library
FITC
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Colon cancer, Retinoblastoma
VEGFR-3 (Human vascular endothelia growth factor receptor 3)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification of a Novel Peptide Ligand of Human Vascular Endothelia Growth Factor Receptor 3 for Targeted Tumour Diagnosis and Therapy
2007
Qin X et al. J Biochem. 2007 Jul 142(1):79-85.

Other

human VEGFR-2(hVEGFR-2) positive HT29 cell line and Y79 cell line
Phage display library
M13 phage /7 mer peptide library
FITC
Additional Detail Fields 3 fields
FITC
The human colon cancer cell line (HT29),Human umbilical vein endothelial cell line (EVC304),Human retinoblastoma cell line (Y79), Human amino cell line (WISH),Human hepatic cancer cell line (HepG2),Human alveolar epithelial cell line (A549) human VEGFR-2(hVEGFR-2) positive HT29 cell line and Y79 cell line
M13 phage / 7-mer peptide library M13 phage /7 mer peptide library