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Peptide record

TPDB40839

RSR Anticancer Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB40839
RSR
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 6-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CRSRKG
Physicochemical Analysis
C26H51N13O8S1
ANDEQHILMFPTWYV
R
705.83
11.32
3
0
0
+3
2.51
-1.933
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
1
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C26H51N13O8S1
705.83
11.32
+3
2.51
-1.933
CRSR-GCRSR-G CendR
Evidence Records 4 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cellor pericytes
Homing
Pancreatic islet carcinoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis
2003
Joyce JA et al. Cancer Cell. 2003 Nov 4(5):393-403.
US 2005/0245445A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Prototypical mouse model of multistage tumorigenesis, RIP1-Tag2 transgenic model of islet cell carcinoma and K14-HPV16 mice
Phage display library
T7 phage/CX7C peptide library
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Homing
Pancreatic tumor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor vasculature address book: identification of stage-specific tumor vessel zip codes by phage display
2003
Rafii S et al. Cancer Cell. 2003 Nov 4(5):331-3.
US 7,598,341 B2

Other

RIP-Tag2 pancreatic tumors in murine model
Phage display library
T7 phage /9-mer cyclic (CX7C) peptide library
Evidence 3 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell,
Homing
gC1q/p32 receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted delivery system and methods of use therefor
2022
US 11512110 B2
US 11512110 B2

Other

Athymic nude mice, ApoE null mice
Phage display library
T7 phage / cyclic Cx7C and linear X7 peptide library
Nanoworms(NWs), polyethylene glycol
Evidence 4 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell,
Homing
gC1q/p32 receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted delivery system and methods of use therefor
2022
US 11512110 B2
US 11512110 B2

Other

Athymic nude mice, ApoE null mice
Phage display library
T7 phage / cyclic Cx7C and linear X7 peptide library
Nanoworms(NWs), polyethylene glycol
Additional Detail Fields 3 fields
Nanoworms(NWs), polyethylene glycol
Prototypical mouse model of multistage tumorigenesis, RIP1-Tag2 transgenic model of islet cell carcinoma and K14-HPV16 mice RIP-Tag2 pancreatic tumors in murine model Athymic nude mice, ApoE null mice
T7 phage/CX7C peptide library T7 phage /9-mer cyclic (CX7C) peptide library T7 phage / cyclic Cx7C and linear X7 peptide library