Peptide record

TPDB40838

Alpha Anticancer Tumor-homing Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB40838
Alpha
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 11-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
C-terminal: C-terminal modification with serine N-terminal: N -terminal modification with serine
Sequence
CRRTNWQGAGC
Physicochemical Analysis
C49H78N20O15S2
DEHILKMFPSYV
RCG
1251.40
9.19
2
0
2
+2
0.28
-1.055
9.09
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
449.50
5
Residue Composition
number
1
A
2
R
1
N
0
D
2
C
0
E
1
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
11
C49H78N20O15S2
1251.40
9.19
+2
0.28
-1.055
C-terminal modification with serine
C(R/Q)L/RT(G/N)XXG(A/V)GC
N -terminal modification with serine
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Cervical cancer
Endothelin A and B

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification using phage display of peptides promoting targeting and internalization into HPV-transformed cell line
2005
Robinson P et al. J Mol Recognit. 2005 Mar-Apr 18(2):175-82.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SiHa (HPV16 integrated human cervical carcinoma)
Phage display library
pC89 phage/CX9C peptide library
Additional Detail Fields 2 fields
SiHa (HPV16 integrated human cervical carcinoma)
pC89 phage/CX9C peptide library