Back to search

Peptide record

TPDB40833

Alpha Anticancer Tumor-homing Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB40833
Alpha
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 11-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
C-terminal: C-terminal modification with serine
Sequence
CRLTGGKGVGC
Physicochemical Analysis
C41H75N15O13S2
ANDEQHIMFPSWY
G
1050.26
9.15
2
0
2
+2
1.01
0.209
61.82
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
11.90
3
Residue Composition
number
0
A
1
R
0
N
0
D
2
C
0
E
0
Q
4
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
11
C41H75N15O13S2
1050.26
9.15
+2
1.01
0.209
C-terminal modification with serine
C(R/Q)L/RT(G/N)XXG(A/V)GC
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Cervical cancer
Endothelin A and B

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification using phage display of peptides promoting targeting and internalization into HPV-transformed cell line
2005
Robinson P et al. J Mol Recognit. 2005 Mar-Apr 18(2):175-82.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SiHa (HPV16 integrated human cervical carcinoma), CaSki (HPV16 integrated human cervical carcinoma)HeLa (HPV18 integrated human cervical carcinoma)
Phage display library
pC89 phage/CX9C peptide library
Additional Detail Fields 2 fields
SiHa (HPV16 integrated human cervical carcinoma), CaSki (HPV16 integrated human cervical carcinoma)HeLa (HPV18 integrated human cervical carcinoma)
pC89 phage/CX9C peptide library