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Peptide record

TPDB40827

iRGD peptide Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB40827
iRGD peptide
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia and TumorHoPe2.0, with an available 3D structural model.
Sequence
CRGDRCPDC
Physicochemical Analysis
C36H61N15O14S3
ANEQHILKMFSTWYV
C
1024.15
6.01
2
2
0
-0
3.82
-1.167
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.21
3
Residue Composition
number
0
A
2
R
0
N
2
D
3
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 2 C: 3 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C36H61N15O14S3
1024.15
6.01
-0
3.82
-1.167
RGD
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Hepatocellular carcinoma
Neuropilin-1

Source & Reference

TumorHoPe2.0
TumorHoPe2
The effect of hydrophilic chain length and iRGD on drug delivery from poly(?Ä??-caprolactone)-poly(N-vinylpyrrolidone) nanoparticles.
2011
Zhu Z et al .Biomaterials 2011 Dec 32(35):9525-35.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
H22 cells
ICR mice (6?ó?é¼?Ç£7 weeks, 23?ó?é¼?Ç£25?é?ág)
Synthetic
Nanoparticles
Additional Detail Fields 3 fields
Nanoparticles
H22 cells
ICR mice (6?ó?é¼?Ç£7 weeks, 23?ó?é¼?Ç£25?é?ág)