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Peptide record

TPDB40825

Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB40825
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CRGDKHADC
Physicochemical Analysis
C37H61N15O14S2
NEQILMFPSTWYV
DC
1004.10
7.00
3
2
1
+0
4.58
-1.356
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
12.45
2
Residue Composition
number
1
A
1
R
0
N
2
D
2
C
0
E
0
Q
1
G
1
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 2 C: 2 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C37H61N15O14S2
1004.10
7.00
+0
4.58
-1.356
RGD
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell and tumor cell
Targeting
Prostate cancer
Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tissue-penetrating delivery of compounds and nanoparticles into tumors
2009
Sugahara KN et al. Cancer Cell. 2009 Dec 8 16(6):510-20.
US 2009/0246133A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Cultured PPC1 human prostate cancer cells, M21 human melanoma cells
Phage display library
T7 phage / CX7C peptide library
Additional Detail Fields 2 fields
Cultured PPC1 human prostate cancer cells, M21 human melanoma cells
T7 phage / CX7C peptide library