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Peptide record

TPDB40817

Anticancer Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB40817
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 7-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CRGDGWC
Physicochemical Analysis
C31H45N11O10S2
ANEQHILKMFPSTYV
CG
795.89
5.95
1
1
1
-0
-0.27
-0.671
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
706.76
2
Residue Composition
number
0
A
1
R
0
N
1
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C31H45N11O10S2
795.89
5.95
-0
-0.27
-0.671
RGD
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Homing
Melanoma
Integrins Alpha- 5 beta -1

Source & Reference

TumorHoPe2.0
TumorHoPe2
The use of RGDGWK-lipopeptide to selectively deliver genes to mouse tumor vasculature and its complexation with p53 to inhibit tumor growth
2009
Samanta S et al. Biomaterials. 2010 Mar 31(7):1787-97.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Mice bearing the aggressive B16F10 tumor
Phage display library
Additional Detail Fields 1 fields
Mice bearing the aggressive B16F10 tumor