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Peptide record

TPDB40816

Anticancer Tumor-homing Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB40816
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia dbACP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 24-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, dbACP, StackTHP, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-CRGDCGGKWCFRVCYRGICYRRCR-NH2
Physicochemical Analysis
C121H190N44O29S6
ANEQHLMPST
RC
2917.48
9.27
7
1
6
+6
0.58
-0.542
28.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
8855
303.52
8
Residue Composition
number
0
A
6
R
0
N
1
D
6
C
0
E
0
Q
4
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 1 C: 6 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
24
C121H190N44O29S6
2917.48
9.27
+6
0.58
-0.542
Amidation
RGD
Acetylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell and Endothelial cell
Homing
Prostate cancer, Melanoma
Integrins

Source & Reference

TumorHoPe2.0
TumorHoPe2
RGD-Tachyplesin inhibits tumor growth
2001
Chen Y et al. Cancer Res. 2001 Mar 15 61(6):2434-8.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
The TSU human prostate cancer cells, B16 melanoma, nontumorigenic cell lines Cos-7, and NIH-3T3
CAMs of 10-day-old chicken embryos, C57BL/6 mice bearing B16 melanoma
Synthetic
Antimicrobial peptide
Additional Detail Fields 3 fields
Antimicrobial peptide
The TSU human prostate cancer cells, B16 melanoma, nontumorigenic cell lines Cos-7, and NIH-3T3
CAMs of 10-day-old chicken embryos, C57BL/6 mice bearing B16 melanoma