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Peptide record

TPDB40792

PEGA Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB40792
PEGA
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CPGPEGAGC
Physicochemical Analysis
C30H47N9O12S2
RNDQHILKMFSTWYV
G
789.88
3.29
0
1
1
-1
2.30
-0.122
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
15.83
2
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
1
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 1 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C30H47N9O12S2
789.88
3.29
-1
2.30
-0.122
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Aminopeptidase P

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease inhibitor:protease sensitive expression system, composition and methods for improving the therapeutic activity and specificity of proteins delivered by bacteria
2022
US 11219671 B1
US 11219671 B1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Salmonella typhimurium
Phage display library
Ph.D-7 Phage Display
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell
Homing
Breast cancer
Aminopeptidase

Source & Reference

TumorHoPe2.0
TumorHoPe2
Aminopeptidase P Mediated Targeting for Breast Tissue Specific Conjugate Delivery
2016
Antoinette Cordova et al. Bioconjug Chem. 2016 Sep 21 27(9):1981-90.

Other

breast cancer cells (MCF-7 and MDA-MB-231), prostate cancer cells (PC-3), and lung cancer cells (A-549)
Female athymic nude mice (nu/nu) 4 to 6 weeks of age
Phage Display Library
PEGA, TAT, and TAMRA moieties
Additional Detail Fields 4 fields
PEGA, TAT, and TAMRA moieties
breast cancer cells (MCF-7 and MDA-MB-231), prostate cancer cells (PC-3), and lung cancer cells (A-549)
Salmonella typhimurium Female athymic nude mice (nu/nu) 4 to 6 weeks of age
Ph.D-7 Phage Display