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Peptide record

TPDB40759

Clone 4 Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB40759
Clone 4
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CKGGRAKDC
Physicochemical Analysis
C35H64N14O12S2
NEQHILMFPSTWYV
CGK
937.10
9.11
3
1
1
+2
3.39
-1.089
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
13.34
2
Residue Composition
number
1
A
1
R
0
N
1
D
2
C
0
E
0
Q
2
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C35H64N14O12S2
937.10
9.11
+2
3.39
-1.089
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Prostate cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Compositions and methods of use of targeting peptides for diagnosis and therapy
2005
US 2005/0191294A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human prostate cancer-derived cell lines MDA-PCa-2b and LNCaP
Athymic nude mice bearing size-matched human DU 145 xenografts
Phage display library
Phage /CX3-10C peptide library
Apoptotic peptide (KLAKLAK)
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

endothelial cell
Homing
prohibitin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Vascular-targeted nanotherapy for obesity: unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery
2012
Md Nazir Hossen et al. J Control Release. 2012 Oct 28 163(2):101-10.

Other

Male C57BL/6 J-DIO mice (body weight >38 g), five week old male wt C57BL/6 J mice
Synthetic
Additional Detail Fields 4 fields
Apoptotic peptide (KLAKLAK)
Human prostate cancer-derived cell lines MDA-PCa-2b and LNCaP
Athymic nude mice bearing size-matched human DU 145 xenografts Male C57BL/6 J-DIO mice (body weight >38 g), five week old male wt C57BL/6 J mice
Phage /CX3-10C peptide library