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Peptide record

TPDB40752

Clone 56 Anticancer Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB40752
Clone 56
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 10-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CIRCNGRCSV
Physicochemical Analysis
C41H75N17O13S3
ADEQHLKMFPTWY
C
1110.33
8.58
2
0
2
+2
1.22
0.250
68.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
11.26
5
Residue Composition
number
0
A
2
R
1
N
0
D
3
C
0
E
0
Q
1
G
0
H
1
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 3 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C41H75N17O13S3
1110.33
8.58
+2
1.22
0.250
NGR
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing (Phage display clone)
Human breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
NGR receptor and methods of identifying tumor homing molecules that home to angiogenic vasculature using same
1998
US 6,180,084 B1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human 435 breast carcinoma cells in mammary fat pad of nude mice
Phage display library
M13 phage /CX3CX3 CX3C peptide library
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell, Epithelial cell, Dendritic cell
Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and compositions using peptides and proteins with C-terminal elements
2019
US 10370245 B2
US 10370245 B2

Other

PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
BALB/c athymic nude mice
Phage Display library
T7 phage display library
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
Additional Detail Fields 4 fields
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
Human 435 breast carcinoma cells in mammary fat pad of nude mice BALB/c athymic nude mice
M13 phage /CX3CX3 CX3C peptide library T7 phage display library