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Peptide record

TPDB40749

LPSBD-2 Anticancer standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB40749
LPSBD-2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 20-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
CHYRVKPKIKRFEKYKGRMW
Physicochemical Analysis
C123H193N37O25S2
ANDQLST
K
2654.24
10.80
9
1
7
+7
5.25
-1.465
34.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
8480
319.49
3
Residue Composition
number
0
A
3
R
0
N
0
D
1
C
1
E
0
Q
1
G
1
H
1
I
0
L
5
K
1
M
1
F
1
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 1 H: 1 I: 1 L: 0 K: 5 M: 1 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
20
C123H193N37O25S2
2654.24
10.80
+7
5.25
-1.465
Free
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

~20% cell survival at 60 µg/ml
Anticancer

Target

Lung Cancer
A-549
Lung

Assay & Model

Cell Proliferation assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2015

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

~40% cell survival at 60 µg/ml
Anticancer

Target

Liver Cancer
Hep3B
Liver

Assay & Model

Cell Proliferation assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2015
Evidence 3 Activity

Activity

Not Available
Anticancer

Target

Leukemia Cancer
THP-1
Blood

Assay & Model

Not Available
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2019