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Peptide record

TPDB40734

Anticancer Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB40734
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 9-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
CGRRAGGSC
Physicochemical Analysis
C30H55N15O11S2
NDEQHILKMFPTWYV
G
865.98
9.19
2
0
1
+2
1.13
-0.467
11.11
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
14.43
3
Residue Composition
number
1
A
2
R
0
N
0
D
2
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C30H55N15O11S2
865.98
9.19
+2
1.13
-0.467
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Prostate cancer
IL-11 receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer
2004
Zurita AJ et al. Cancer Res. 2004 Jan 15 64(2):435-9.
WO0402020722A2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human primary and metastatic prostate cancer samples,cancer-derived cell lines MDA-PCa-2b and LNCaP
Phage display library
Stage-specific expression of IL-11Ralpha during disease progression
Additional Detail Fields 1 fields
Human primary and metastatic prostate cancer samples,cancer-derived cell lines MDA-PCa-2b and LNCaP