TPDB

3D PDB MODEL

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TPDB ID TPDB40682

Activity

Anticancer Tumor-homing Peptides

Activity_category_statistics

Cancer-related peptides

Database_Source

Peptipedia StackTHP StackTHPred TumorHoPe2.0

Sequence_Type

standard

Has_Modification No

Description A 7-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.

Sequence

CASLSCR

FASTA

>TPDB40682|Anticancer;Tumor-homing Peptides|length=7
CASLSCR

Formula C27H50N10O10S2

Absent Amino Acids NDEQGHIKMFPTWYV

Common Amino Acids CS

Mass 738.88

PI 8.30

Basic Residues 1

Acidic Residues 0

Hydrophobic Residues 2

Net Charge +1

Boman Index -0.14

Hydrophobicity 0.643

Aliphatic Index 70.00

Half Life

Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 125

Absorbance 280nm 16.92

Polar Residues 4

number

1

A

1

R

0

N

0

D

2

C

0

E

0

Q

0

G

0

H

0

I

1

L

0

K

0

M

0

F

0

P

2

S

0

T

0

W

0

Y

0

V

Amino Acid Distribution

A: 1 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0

Length

7

Formula

C27H50N10O10S2

Mass

738.88

PI

8.30

Net Charge

+1

Boman Index

-0.14

Hydrophobicity

0.643

Evidence 1 Activity

Activity

Detail Source Activity Tumor-homing Peptides

Target

Homing or Targeting Homing

Target Tumor Prostate cancer

Source & Reference

Database Source TumorHoPe2.0

Source TumorHoPe2

Title Lymphatic zip codes in tumors and pre -malignant lesions

Year 2007

Patent US 2007/0219134 A1

Other

Source Activity Label	Source Definition
Tumor-homing Peptides	TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.

InVivo Model TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors

Source Type Phage display library

Evidence 2 Activity

Activity

Detail Source Activity Tumor-homing Peptides

Target

Homing or Targeting Homing

Target Tumor Premalignant prostate cancer

Source & Reference

Database Source TumorHoPe2.0

Source TumorHoPe2

Title Lymphatic zip codes in tumors and pre -malignant lesions

Year 2007

Patent US 2007/0219134 A1

Other

InVivo Model TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors

Source Type Phage display library

Evidence 3 Activity

Activity

Detail Source Activity Tumor-homing Peptides

Target

Homing or Targeting Homing

Target Tumor Malignant prostate cancer

Source & Reference

Database Source TumorHoPe2.0

Source TumorHoPe2

Title Lymphatic zip codes in tumors and pre -malignant lesions

Year 2007

Patent US 2007/0219134 A1

Other

InVivo Model TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors

Source Type Phage display library

InVivo_Model

TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors