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Peptide record

TPDB40666

Anticancer Tumor-homing Peptides modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB40666
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia TumorHoPe2.0
modified_plain
Yes
A 18-aa modified multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia and TumorHoPe2.0, with an available 3D structural model.
C-terminal: FITC labeling N-terminal: Amidation
Sequence
BCDSDSDITWDQLWDLMK
Physicochemical Analysis
C89H131N21O32S2
ARNEGHFPYV
D
2071.26
3.31
1
5
6
-4
2.52
-0.694
65.00
Mammalian: Yeast: E.coli:
11000
531.08
5
Residue Composition
number
0
A
0
R
0
N
5
D
1
C
0
E
1
Q
0
G
0
H
1
I
2
L
1
K
1
M
0
F
0
P
2
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 5 C: 1 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 2 K: 1 M: 1 F: 0 P: 0 S: 2 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
18
C89H131N21O32S2
2071.26
3.31
-4
2.52
-0.694
FITC labeling
Amidation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell,endothelial cell
Homing
Human prostrate cancer, lewis lung carcinoma
E-selectin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Nanoparticles for the optical imaging of tumor E-selectin
2005
Funovics M et al. Neoplasia. 2005 Oct 7(10):904-11.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Activated HUVEC, Human prostrate biopsies,llc cell line
Mouse xenograft model of LLC
Synthetic
FITC , nanoparticle CLIO(Cy5.5)
Additional Detail Fields 3 fields
FITC , nanoparticle CLIO(Cy5.5)
Activated HUVEC, Human prostrate biopsies,llc cell line
Mouse xenograft model of LLC