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Peptide record

TPDB40660

Z8 Anticancer standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB40660
Z8
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF
standard
No
A 21-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
AWKKWAKAWKWAKAKWWAKAA
Physicochemical Analysis
C132H186N34O22
RNDCEQGHILMFPSTYV
A
2601.14
11.29
7
0
14
+7
-5.53
-0.871
38.10
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
33000
1268.67
0
Residue Composition
number
8
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
7
K
0
M
0
F
0
P
0
S
0
T
6
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 6 Y: 0 V: 0
Chemical Descriptors
21
C132H186N34O22
2601.14
11.29
+7
-5.53
-0.871
Free
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

EC50
EC50 =19 µM
Anticancer
19 µM

Target

Skin Cancer
Meth A
Skin

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 =14 µM
Anticancer
14 µM

Target

Breast Cancer
MT-1
Breast

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011
Evidence 3 Activity

Activity

EC50
EC50 =23 µM
Anticancer
23 µM

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011