Back to search

Peptide record

TPDB40650

RP7 Anticancer standard
7 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB40650
RP7
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 7-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
ATRQPNH
Physicochemical Analysis
C33H54N14O11
DCEGILKMFSWYV
ARNQHPT
822.88
11.05
2
0
1
+1
3.19
-2.171
14.29
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
0
E
1
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C33H54N14O11
822.88
11.05
+1
3.19
-2.171
Free
L
Linear
Free
Anticancer
RAGE(receptor for advanced glycation end product) inhibitor
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 24.5 µM
Anticancer
24.5 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 29.9 µM
Anticancer
29.9 µM

Target

Breast Cancer
BT-549
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023