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Peptide record

TPDB40643

Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB40643
Anticancer Tumor-homing Peptides
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 Peptipedia iACP-DRLF pep-lab StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
ASSSYPLIHWRPWAR
Physicochemical Analysis
C86H123N25O20
NDCEQGKMFTV
S
1827.08
11.16
3
0
7
+2
-1.98
-0.600
65.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
12490
683.61
4
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
1
L
0
K
0
M
0
F
2
P
3
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 1 K: 0 M: 0 F: 0 P: 2 S: 3 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
15
C86H123N25O20
1827.08
11.16
+2
-1.98
-0.600
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Angiogenic endothelial cell
Homing
Melanoma
VEGF

Source & Reference

TumorHoPe2.0
TumorHoPe2
Anti-neovascular therapy using novel peptides homing to angiogenic vessels
2002
Oku N et al. Oncogene. 2002 Apr 18 21(17):2662-9.
US 6,753,310 B1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor
Phage display library
M13 phage/15 mer peptide library
No specific binding to endothelial cells in the islet cell tumor in humans.
Additional Detail Fields 2 fields
5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor
M13 phage/15 mer peptide library