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Peptide record

TPDB40640

P6 Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB40640
P6
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
ARVSFWRYSSFAPTY
Physicochemical Analysis
C88H120N22O22
NDCEQGHILKM
S
1838.06
10.25
2
0
8
+2
-3.66
-0.253
32.67
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
8480
461.36
6
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
1
P
3
S
1
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 1 S: 3 T: 1 W: 1 Y: 2 V: 1
Chemical Descriptors
15
C88H120N22O22
1838.06
10.25
+2
-3.66
-0.253
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Breast cancer
Gal beta1 --> 3GalNAc alpha disaccharide

Source & Reference

TumorHoPe2.0
TumorHoPe2
Characterization of peptides that bind the tumor-associated Thomsen-Friedenreich antigen selected from bacteriophage display libraries
1997
Peletskaya EN et al. J Mol Biol. 1997 Jul 18 270(3):374-84.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast carcinoma cell line MDA-MB-435
Phage display library
f3 Bacteriophage/ 15-mer peptide library
Additional Detail Fields 2 fields
Human breast carcinoma cell line MDA-MB-435
f3 Bacteriophage/ 15-mer peptide library