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Peptide record

TPDB40629

Clone G3-A18 Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB40629
Clone G3-A18
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
APRPGPWLWSNADSV
Physicochemical Analysis
C76H109N21O21
CEQHIKMFTY
P
1652.83
6.78
1
1
6
-0
-0.45
-0.567
58.67
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
11000
665.53
3
Residue Composition
number
2
A
1
R
1
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
3
P
2
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 3 S: 2 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
15
C76H109N21O21
1652.83
6.78
-0
-0.45
-0.567
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell and tumor cell
Targeting
Tumor metastasis
Galectin-3

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion
2005
Zou J et al. Carcinogenesis. 2005 Feb 26(2):309-18.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 5
Phage display library
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library
Additional Detail Fields 2 fields
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 5
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library