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Peptide record

TPDB40614

14V5K Anticancer standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB40614
14V5K
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 23-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
ALWKKILKNAGKAVLNEINQIVQ-NH2
Physicochemical Analysis
C119H203N33O31
RDCHMFPSTY
K
2592.12
10.55
4
1
12
+3
3.58
0.035
140.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
212.18
5
Residue Composition
number
3
A
0
R
3
N
0
D
0
C
1
E
2
Q
1
G
0
H
3
I
3
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 3 D: 0 C: 0 E: 1 Q: 2 G: 1 H: 0 I: 3 L: 3 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
23
C119H203N33O31
2592.12
10.55
+3
3.58
0.035
Amidation
L
Linear
Free
Antimicrobial and Anticancer
Dermaseptin-SS1- Analog
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 8.1 µM
Anticancer
8.1 µM

Target

Lung Cancer
H-838
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 6.1 µM
Anticancer
6.1 µM

Target

Lung Cancer
H-460
Lung

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023