Back to search

Peptide record

TPDB40587

NL1.3 Anticancer Tumor-homing Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB40587
NL1.3
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 24-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
AEGEFLMWGGSHWLEYWYEGDPAK
Physicochemical Analysis
C135H176N30O38S1
RNCQITV
EG
2859.12
4.00
2
5
11
-4
1.63
-0.750
40.83
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
19480
681.33
3
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
4
E
0
Q
4
G
1
H
0
I
2
L
1
K
1
M
1
F
1
P
1
S
0
T
3
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 4 Q: 0 G: 4 H: 1 I: 0 L: 2 K: 1 M: 1 F: 1 P: 1 S: 1 T: 0 W: 3 Y: 2 V: 0
Chemical Descriptors
24
C135H176N30O38S1
2859.12
4.00
-4
1.63
-0.750
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
HER2(Human epidermal growth factor receptor 2)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted gene transduction of mammalian cells expressing the HER2/neu receptor by filamentous phage
2001
Urbanelli L et al. J Mol Biol. 2001 Nov 9 313(5):965-76.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast carcinoma SK-Br-3, human ovarian carcinoma SKOV3, human melanoma MeWo and mouse fibroblast NIH3T3 cells
Phage display library
T7 phage/12 mer peptide library
Additional Detail Fields 2 fields
Human breast carcinoma SK-Br-3, human ovarian carcinoma SKOV3, human melanoma MeWo and mouse fibroblast NIH3T3 cells
T7 phage/12 mer peptide library