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Peptide record

TPDB40584

NL1.4 Anticancer Tumor-homing Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB40584
NL1.4
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 24-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
AEGEFGHWCDQHWLQYWYEGDPAK
Physicochemical Analysis
C137H174N34O39S1
RNIMSTV
EGW
2953.15
4.27
3
5
9
-4
3.37
-1.258
24.58
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
19480
659.63
5
Residue Composition
number
2
A
0
R
0
N
2
D
1
C
3
E
2
Q
3
G
2
H
0
I
1
L
1
K
0
M
1
F
1
P
0
S
0
T
3
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 2 C: 1 E: 3 Q: 2 G: 3 H: 2 I: 0 L: 1 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 3 Y: 2 V: 0
Chemical Descriptors
24
C137H174N34O39S1
2953.15
4.27
-4
3.37
-1.258
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
HER2(Human epidermal growth factor receptor 2)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted gene transduction of mammalian cells expressing the HER2/neu receptor by filamentous phage
2001
Urbanelli L et al. J Mol Biol. 2001 Nov 9 313(5):965-76.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast carcinoma SK-Br-3, human ovarian carcinoma SKOV3, human melanoma MeWo and mouse fibroblast NIH3T3 cells
Phage display library
T7 phage/12 mer peptide library
Additional Detail Fields 2 fields
Human breast carcinoma SK-Br-3, human ovarian carcinoma SKOV3, human melanoma MeWo and mouse fibroblast NIH3T3 cells
T7 phage/12 mer peptide library