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Peptide record

TPDB40579

P05 Anticancer standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB40579
P05
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 12-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
ADDGRPFPQVIK
Physicochemical Analysis
C60H95N17O18
NCEHLMSTWY
DP
1342.52
6.90
2
2
4
-0
4.21
-0.767
65.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
2
D
0
C
0
E
1
Q
1
G
0
H
1
I
0
L
1
K
0
M
1
F
2
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C60H95N17O18
1342.52
6.90
-0
4.21
-0.767
Free
L
Linear
Free
Anticancer
Aldolase A fragment
Evidence Records 2 records
Evidence 1 Activity

Activity

Relative viability
Relative viability = 0.85 at 50 µg/ml
Anticancer

Target

Bone Cancer
MG-63
Bone

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Relative viability
Relative viability = 0.98 at 50 µg/ml
Anticancer

Target

Bone Cancer
U-2 OS
Bone

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023