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Peptide record

TPDB40571

hP4 Anticancer standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB40571
hP4
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 25-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
AAVPIVNLKDELLFPSWEALFSGSE
Physicochemical Analysis
C128H194N28O38
RCQHMTY
L
2733.11
3.69
1
4
13
-3
2.97
0.432
113.20
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
201.24
4
Residue Composition
number
3
A
0
R
1
N
1
D
0
C
3
E
0
Q
1
G
0
H
1
I
4
L
1
K
0
M
2
F
2
P
3
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 1 C: 0 E: 3 Q: 0 G: 1 H: 0 I: 1 L: 4 K: 1 M: 0 F: 2 P: 2 S: 3 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
25
C128H194N28O38
2733.11
3.69
-3
2.97
0.432
Free
L
Linear
Free
Antiangiogenesis
Human endostatin peptides
Evidence Records 1 records
Evidence 1 Activity

Activity

No inhibition at 7 mg/kg/d
Anticancer

Target

Pancreatic Cancer
BxPC-3
Pancreatic

Assay & Model

Matrigel Assay
672-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.