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Peptide record

TPDB40563

HMM-ID Anticancer standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB40563
HMM-ID
Anticancer
Cancer-related peptides
CancerPPD 2.0 dbACP
standard
No
A 34-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0 and dbACP, with an available 3D structural model.
Sequence
AAEKEFIKYPYPTPLQYQQLATRLKVEKKLVRRW
Physicochemical Analysis
C197H312N52O49
NDCGHMS
K
4192.96
10.37
8
3
15
+5
8.09
-0.844
83.24
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
9970
237.78
8
Residue Composition
number
3
A
3
R
0
N
0
D
0
C
3
E
3
Q
0
G
0
H
1
I
4
L
5
K
0
M
1
F
3
P
0
S
2
T
1
W
3
Y
2
V
Amino Acid Distribution
A: 3 R: 3 N: 0 D: 0 C: 0 E: 3 Q: 3 G: 0 H: 0 I: 1 L: 4 K: 5 M: 0 F: 1 P: 3 S: 0 T: 2 W: 1 Y: 3 V: 2
Chemical Descriptors
34
C197H312N52O49
4192.96
10.37
+5
8.09
-0.844
Free
L
Linear
Free
Anticancer
Red Sea Brine
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 100.5 µg/ml
Anticancer
100.5 µg/mL

Target

Osteosarcoma
U2OS
Bone

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2024

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.