Back to search

Peptide record

TPDB39722

Neurotoxin Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB39722
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2 and ToxinPred 3.0, with an available 3D structural model.
Sequence
CCEWPCHHGCIPCCY
Physicochemical Analysis
C73H100N20O19S6
ARNDQLKMFSTV
C
1754.08
5.99
2
1
3
-1
0.31
0.253
26.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
7365
419.88
7
Residue Composition
number
0
A
0
R
0
N
0
D
6
C
1
E
0
Q
1
G
2
H
1
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 6 E: 1 Q: 0 G: 1 H: 2 I: 1 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
15
C73H100N20O19S6
1754.08
5.99
-1
0.31
0.253
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin with unknown target (Probable). Possibly targets ion channels (Probable). In vivo, intraperitoneal injection into fish provokes paralysis after 5 minutes (By similarity). {ECO:0000250|UniProtKB:P0CH15, ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus inscriptus (Engraved cone)
Neurotoxin Ion channel impairing toxin
Probable neurotoxin with unknown target (Probable). Possibly targets ion channels (Probable).
Conotoxin In1746 (Conotoxin In1762)
cone snail
Conotoxin M superfamily
Evidence at protein level
Amidation Direct protein sequencing Disulfide bond Hydroxylation Ion channel impairing toxin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:33732044}.
Additional Detail Fields 7 fields
Amidation Direct protein sequencing Disulfide bond Hydroxylation Ion channel impairing toxin Neurotoxin Secreted Toxin
Neurotoxin Ion channel impairing toxin
Evidence at protein level
Conotoxin M superfamily
Conotoxin In1746 (Conotoxin In1762)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:33732044}.
cone snail