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Peptide record

TPDB39413

Neurotoxin Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB39413
Neurotoxin Toxicity
Toxicity and safety peptides
NTxPred2 Peptipedia ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Neurotoxin and Toxicity) peptide sequence curated from NTxPred2, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
YRRRQCPPWCSGEPCRKGTC
Physicochemical Analysis
C98H155N35O27S4
ANDHILMFV
RC
2383.77
9.24
5
1
2
+4
4.72
-1.410
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
7240
303.72
8
Residue Composition
number
0
A
4
R
0
N
0
D
4
C
1
E
1
Q
2
G
0
H
0
I
0
L
1
K
0
M
0
F
3
P
1
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 4 E: 1 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 3 S: 1 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
20
C98H155N35O27S4
2383.77
9.24
+4
4.72
-1.410
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Californiconus californicus (California cone) (Conus californicus)
Neurotoxin
Conotoxin Cl14b (Conotoxin Cl14.3)
cone snail
Evidence at protein level
Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:20363338}.
Additional Detail Fields 6 fields
Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Conotoxin Cl14b (Conotoxin Cl14.3)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:20363338}.
cone snail